2011 German Escherichia coli outbreak: Prophage analysis of close-assembled TY2482 against 55989 using PHAST
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چکیده
منابع مشابه
The 2011 Shiga toxin-producing Escherichia coli O104:H4 German outbreak: a lesson in genomic plasticity.
Escherichia coli is known as a versatile bacterial species encompassing both commensal and intraintestinal and extraintestinal pathogenic strains. An E. coli genome contains between 4200 and 5500 genes, with <2000 genes being conserved among all strains of the species (the core genome). Also, the pan-genome (i.e. all of the non-orthologous genes found in the species) consists of almost 20 000 g...
متن کامل2011 German Escherichia coli outbreak: Alignment-free whole-genome phylogeny by feature frequency profiles
Introduction: Accuracy of SNP-based whole-genome phylogeny reconstruction relies heavily on quality of sequence alignment which is particularly hindered by poorly assembled genomes. Alignment-free methods might provide additional insights. Here, we constructed a wholegenome phylogeny of 9 outbreak isolates against existing E. coli genomes using the alignment-free feature frequency profile (FFP)...
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Introduction The outbreak of Shiga Toxin producing Escherichia coli O104:H4 linked to bean sprouts led to over 3800 confirmed cases of illness that included more than 823 cases of Haemolytic Uremic Syndrome (HUS) and 44 deaths (Frank et al., 2011). Although it appeared that the O104:H4 serotype came from nowhere the pathogen had actually been isolated in Germany 10 years ago. The outbreak in Ge...
متن کاملCyclic-di-GMP signalling and biofilm-related properties of the Shiga toxin-producing 2011 German outbreak Escherichia coli O104:H4
In 2011, nearly 4,000 people in Germany were infected by Shiga toxin (Stx)-producing Escherichia coli O104:H4 with > 22% of patients developing haemolytic uraemic syndrome (HUS). Genome sequencing showed the outbreak strain to be related to enteroaggregative E. coli (EAEC), suggesting its high virulence results from EAEC-typical strong adherence and biofilm formation combined to Stx production....
متن کاملProphage induction of Escherichia coli (lambda) by N-nitrosamines.
Carcinogenic N-nitrosamines were tested for their ability to induce lambda in a lysogenic strain of Escherichia coli K-12 (58-161 F+ Dimethylnitrosamine, di-n-propylnitrosamine, methyl-n-propylnitrosamine, and N-nitrosopiperidine were shown to be inducers of prophage.
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ژورنال
عنوان ژورنال: Nature Precedings
سال: 2011
ISSN: 1756-0357
DOI: 10.1038/npre.2011.6110